Ex vivo electrochemical measurement of glutamate release during spinal cord injury
نویسندگان
چکیده
منابع مشابه
Ex vivo diffusion tensor imaging of spinal cord injury in rats of varying degrees of severity.
The aim of this study was to characterize magnetic resonance diffusion tensor imaging (DTI) in proximal regions of the spinal cord following a thoracic spinal cord injury (SCI). Sprague-Dawley rats (n=40) were administered a control, mild, moderate, or severe contusion injury at the T8 vertebral level. Six direction diffusion weighted images (DWIs) were collected ex vivo along the length of the...
متن کاملNovel injury mechanism in anoxia and trauma of spinal cord white matter: glutamate release via reverse Na+-dependent glutamate transport.
Spinal cord injury is a devastating condition, with much of the clinical disability resulting from disruption of white matter tracts. Recent reports suggest a component of glutamate excitotoxicity in spinal cord injury. In this study, the role of glutamate and mechanism of release of this excitotoxin were investigated in rat dorsal column slices subjected to 60 min of anoxia or 15 sec of mechan...
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ژورنال
عنوان ژورنال: MethodsX
سال: 2019
ISSN: 2215-0161
DOI: 10.1016/j.mex.2019.08.008